- Title
- Stratified medicine for acute and chronic coronary syndromes: A patient-tailored approach
- Creator
- Montone, Rocco A.; Ford, Thomas J.; Galli, Mattia; Rinaldi, Riccardo; Bland, Adam; Morrow, Andrew; Angiolillo, Dominick J.; Berry, Colin; Kaski, Juan Carlos; Crea, Filippo
- Relation
- Progress in Cardiovascular Diseases Vol. 85, Issue July-August 2024, p. 2-13
- Publisher Link
- http://dx.doi.org/10.1016/j.pcad.2024.06.003
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2024
- Description
- The traditional approach to management of cardiovascular disease relies on grouping clinical presentations with common signs and symptoms into pre-specified disease pathways, all uniformly treated according to evidence-based guidelines (“one-size-fits-all”). The goal of precision medicine is to provide the right treatment to the right patients at the right time, combining data from time honoured sources (e.g., history, physical examination, imaging, laboratory) and those provided by multi-omics technologies. In patients with ischemic heart disease, biomarkers and intravascular assessment can be used to identify endotypes with different pathophysiology who may benefit from distinct treatments. This review discusses strategies for the application of stratified management to patients with acute and chronic coronary syndromes.
- Subject
- precision medicine; stratified medicine; acute coronary syndrome; chronic coronary syndrome; Ischemia and Non-Obstructed Coronary Artery (INOCA); Myocardial Infarction with Non-Obstructed Coronary Arteries (MINOCA)
- Identifier
- http://hdl.handle.net/1959.13/1510354
- Identifier
- uon:56390
- Identifier
- ISSN:0033-0620
- Rights
- x
- Language
- eng
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